Difference in results Neo4j analytics versus R network analytics

I see many examples of using R for data analytics, even graph analytics without a graph database. What is the difference in results of analysis using graph analytics in Neo4j and R network analysis without a graph database? This is an example of R network analysis without a graph database - https://www.jessesadler.com/post/network-analysis-with-r/.
In that example, you create a matrix, a true graph database.